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P Crosstalk between allergic and autoimmune reactions: Schmidt1,2; N. Lorenz1; V. Raker1,2; K.

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Currently, preventive and therapeutic strategies are avoidance of the allergen or treatment of clinical symptoms, respectively. Epidemiological studies noted a lower prevalence of ACD in individuals with autoimmune diseases like type I diabetes, psoriasis or rheumatoid arthritis as compared to healthy individuals. However, the clinical relevance of this inverse correlation and the underlying immune mechanisms have not been evaluated so far. We compared the impact of the diabetic phenotype on AGG AIPDLOG25 development of the CHS reaction in diabetic vs. In summary, our data indicate AGG AIPDLOG25 the manifestation of an autoimmune disease like diabetes mellitus type I circumvents the development of CHS in mice and, therefore, confirmed the epidemiological data of a reduced susceptibility for ACD in patients suffering from autoimmune diseases.


The identification of a novel link between the development of allergic and autoimmune diseases may result in new preventive strategies for inflammatory disorders. AGG AIPDLOG25 S. Ritz3; D. Becker4; W. Ruf2; M.

Schmidgen1,2; K. Despite AGG AIPDLOG25 in elucidating the pathogenesis of the ACD, the development of new targets for specific and effective therapeutic strategies is still at initial stages.

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After informed consent of the patients, contact allergy AGG AIPDLOG25 elicited using a patch test on the back of the patients with Vaseline as control. The formation of a regular inflammatory reaction was verified by histological hematoxylin and eosin staining.

We hope that AGG AIPDLOG25 study contributes to the identification of novel therapeutics that may improve the treatment options for patients with cutaneous inflammatory disorders. P Nasal microbiome under natural pollen exposure conditions: Rauer1; C.

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Reiger1; T. Nussbaumer1,2; A. Obersteiner2; M.


Rothballer2; F. Damialis1; C. Neumann1; S. The incidence of allergic airway diseases has been increasing over the last decades. This has been partly attributed to higher AGG AIPDLOG25 longer exposure to airborne pollen, which is a major cause for respiratory symptoms in sensitized patients. Imbalances and changes in mucosal microbiota parallel allergic disease outcome, with the cause effect relationship being undefined.


We have recently shown that pollen harbor a distinctive microbiome. Interestingly, Alcaligenes faecalis was found to be present in both AGG AIPDLOG25 but decreased during the pollen season. Conclusion and outlook: In healthy subjects, the overall nasal microbiome seems to be stable independent of pollen exposure, when compared against the microbial diversity of sensitized patients which decreases during the pollen season. Vera AGG AIPDLOG25 M.

Magerl; M. Maurer; J. One of the hallmark features of chronic AGG AIPDLOG25 is the release of preformed mediators including proteases such as tryptase and chymase from activated mast cells MCs. FALSE AGG Software n/a n/a Alabama n/a USA AGG aipdlogexe aipdlogexe aipdlogexe N N N.

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